Go to Menu > Setup > System > Expert settings > Hotkey where you can edit Hotkey's. This nice feature gives you full control over your hotkeys and how they are defined.
When you have opened the Hotkey feature as described above and press the key on you remote control you want to edit. As an example I will use the EPG key on your remote control press this key on your remote control and OpenPLi will jump to it.
In screen above, on the left (below the OpenPLi bootlogo), there is show event details this is the default function when you press the EPG button. On the right there are categories you can add to this key. If you press OK on the + it will open up the the possibilities within a category. When you do this for the catagorie EPG, the third is Show event details when you press it the function is removed from the EPG button. When you now select and press Graphical Multi EPG this will be programmed in for the EPG key, don't forget to save (green button).
Note: you can toggle between left (attached function) and right (list) with Bouquets/Channel +/- buttons.
To delete a programmed key, use the CH+/CH- button to select the programmed key and then press OK to delete the programmed key.